"Doesn't Matter, Still Fuck."
A phrase originating on the internet obviously, around reddit and the usual imageboards. Probably a takeoff of doesn't matter had sex.
Used as a simplistic way of saying that despite whatever faults, flaws, or infections are mentioned while discussing a person, you would still gladly fuck them.
"Kelly's alright from a distance but up close she's got dandruff and crazy halitosis."