Top Definition
Most well known song by the heavy metal band Pantera, as well as being their first single. This song showcases Dimebag Darrel's style of guitar playing, and was the band's first release since they left behind their "glam metal" image of the mid to late 80's, and subsequently formed the sub genre of heavy metal that came to be known as groove metal
Cowboys from Hell is arguably Pantera's finest song, a real headbanger!
by Earthsnake March 15, 2009
Largely considered to be the hardest song on the original Guitar Hero.
Hey, I finally beat Cowboys from Hell today!
by HeavyD2 September 21, 2008
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