Top Definition
Cotton Mouse: 1. A cylindrical absorbant piece of cotton with a string for removal used during the female menstrual period to absorb blood, uteran lining, unused baby eggs, etc. 2. Tampon.
Man to his friend at Hooters:

"Damn, trim's killer. Exept for that cotton mouse peekin' out her short-shorts. Weak."
by Natalie February 01, 2004

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