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Being in a generally grumpy mood and/ or getting worked up and frustrated over something. See also moated
What's wrong with Chris? I don't know, he's all butt sore over something.

Dude, don't get butt sore!
by The Cobra January 18, 2005
being upset about something trivial
Michael J is so butt sore right now
by beepboopimarobit January 25, 2009
Used to describe someone who has trouble taking a joke, especially a joke that most people find funny.
Dennis was buttsore, he wanted to remove a definition that used his name on urbandictionary.com.
by Peter Bitter June 01, 2004