Top Definition
Mental and Physical breakdown following the failure to win a much-hyped reality talent show.
eg. Susan Boyle on 'Britain's got Talent.

Andy: Did you see that Big Brother has-been freakout in Wallmart yesterday?

Tom: Yeah ... Boyle's Syndrome again .. he'll be in a psych ward come Christmas.
by Hangdog68 June 01, 2009
5 Words related to Boyle's Syndrome

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