"Hey Ricky, dating that chick that has Biggy Smalls Syndrome will ultimately lead to your downfall."
by T.L. July 5, 2005
Yo mama got one big titty and one little titty, they call the bitch biggie smalls! - Biggie Smalls syndrome
by Chips and subs November 15, 2010
by El_Karnicero January 31, 2008