An expression used when getting drunk off of Jim Beam, referring to Star Trek. When one says "Beam me up" They usually intend to get drunk to the point that they may as well actually be "beamed up," because they intend to be completely incoherent, and trying to carry out a real conversation with them would be almost impossible.
Scotty: Dude I just got a couple bottles of Jim Beam!
Ted: Shit dude! Beam me up!