Top Definition
Best Friends made through the diagnosis of brain tumors. Brain Tumor Friends Forever!!
I met Nikki and Melissa thru the brain tumor association and it didn't take long for us to be BTFF.
#best friends #bff #best friends forever #brain tumor #brain tumor associtation
by ChickenMuscles June 03, 2010
Best Teacher Friend Forever
Mr. Johnson and I sometimes hang outside of class. He's my BTFF.
#bff #teacher #forever #teacher friend #best friend
by Mr. Johnson's Daughter November 02, 2013
Be the fuckung friend.
btff Be the fucking friend
by porno fonen April 28, 2004
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