Top Definition
Is an acronym for "Am I missing something syndrome"

Usually felt when you are restricted from going to a party due to any cause.

If you're sitting at home wondering, "Am I missing something" chances are, you are.
Person 1: You missed a huge party last night, Brandon lit himself on fire
Person 2: Fuck me, Had to go to my cousins, was suffering from AIMSS all night.
by MAJESTY604 April 14, 2011
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