Top Definition
A slutty girl, most likely infected with AIDS or another STD.
Hey, are you gonna try to hook up with Sarah? I heard she's really easy.
No way, I'm steering clear of that AIDS grenade.
by The Pantangler May 11, 2011
1 more definition
AIDS Grenade (noun): When you start hanging out with a chick who has AIDS, just so that everyone will think you close, and then when your enemies come out of the woodwork to bang her, they get AIDS.
Dude: 'Does Jim really bang that junkie chick who's always hanging around?'

Bro: 'Naw, she's an AIDS Grenade.'
by doktorj November 24, 2014

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