Basically it means to shrug one's shoulders
over msn, or similar program
Student 1: dude, do we have any homework due tomorrow?

Student 2: \_(O_o)_/

Student 1: Some help you are
by Jono8825 May 17, 2009
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When online, used to express a state of utter wtfness, or when you simply cannot believe the stupidity of what the person above has just said. It kind of reminds me of a paralysed frog.
Person: OMGWTFBBQ, lawlorz i sooooooooooooooooo pwned
joo /\/00b!!!1 1!1!1!!1im sooo awsum!!111!11one!!! !11!!!!eleven!!! "11!"211! LOLOOLOLOLOLOLOLOLOLOL LOLOLLOLOLLOLIPOP

You: O_O
by Master of Contradictions September 24, 2007
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When you are compelled to say something, but lack the subject matter.

Used in place of " Ok... " or " Right... ", etc.
"Dude, I just killed my mother."
"o_o..."
by CoreyD April 3, 2005
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A emoticon expressing complete, what the hell-ness. Used when one can't beileve the retardation and non sense that is going on. Used a lot by people in chat rooms that are annoyed by the useless gabber of teenyboppers and the pervo requests for p2p's by pedos.
Chat room idiot #1; Omg omg look at his myspace pics! CR idiot #2; He is like, so, tottaly hot! CR idiot #3; Any dirty girls wanna role play? P2p me ;0. Person in shock; O_o, Dudes, WTF?
by The Drunk From Omaha September 5, 2009
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"foobar1: my puter doesnt open this prog
foobar2: o_O"
"foobar1: o_O thats an odd error"

AKA: O_o, =o
by Ruben Mothballs January 26, 2003
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A sign that means blink, as in dumbfounded or have no other words.
USer: (thinks).......o_O what?
by One (1) Crazy Idiot December 22, 2004
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Going chombie or expressing extreme exhaustion
Dude I was like whoa then you were like whoa then I was like (~O_O)~
by syotsu July 16, 2011
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