Commonly used as a word for "For Sure" or Yes I Agree fully.
Cracker1: Yoh! I'd tap that ass anyday.
Wannabe Cracker: Fo' Sho!
by Shak April 19, 2003
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A shot to the head.

It is said in the tv show Gangland when Do was describing a way to do a hit.
"We had a, uh two guys, we called them Double Trouble. One person would hit you in the body, which would drop you, and the other person would put the what we call the fo' sho'."
by daboodeef179 September 23, 2011
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That one incredibly hard part in Love Rap in Rhythm Heaven Fever that makes you want to throw your Wii Remote at the goddamn TV.
"Dude, what happened?"
"I lost to the fo' sho' part."
by dragonman9001 October 31, 2019
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An urban term meaning 'for sure', hip hop language.
you going to that game concert tonight G? ''Fo Sho''
by Bailzz January 6, 2007
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'For Sure' or Most definetly... Also meaning of course, or yes, yeah, ja, si, mmm hmmm , uh huh...
>Yo' Homme you wanna hit up that joint t'night?
>'Oh Fo' Sho' Dawg...
by JB February 13, 2003
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