Can also mean a musician of great skill. Often coupled with "bad" as in "bad motherfucker". Can be an extreme compliment in certain circumstances.
Man, Prince is a motherfucker on that (guitar/bass/keyboard/piano/drumkit)
by jedilaw March 26, 2003
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Someone who would sell out even his own mother to get ahead.
I can't believe he would say that about his mom he is a motherfucker!
by FM Punk October 18, 2018
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You're father.
Son: Hey motherfucker, how was mom during my conception?
by SomeRetard101 November 28, 2020
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This term was originally used during slavery or by slaves. The salve master would come to the slave "house" and take liberties with the female slaves. Though the term was not usually said to the "masters" face, if it was said that the motherfucker was coming it was known what was meant.

(The term applied to slave masters or anyone that had authority over the slaves. Slave Masters, Their Sons and overseers).
Here comes the motherfucker again. The motherfucker came last night.
by Muquit January 9, 2012
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Term derived by the psychoanalyst Sigmund Freud, about innate desires to kill the father and fuck the mother.
Do you know that Oedipus story?
Yeah, Oedipus was a motherfucker!
by Terry Richards 2008 May 9, 2008
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When a group event becomes lame due to mixed circles.
My birthday party turned into a motherfuckation when Sean, his bitchy wife and their spoiled ass kids showed up. Who invited them anyways?
by Dubsmith7 October 15, 2014
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1.A very annoying, obnoxious, mean person. Similar to words such as Fucker, Douchebag, Asshole, Jerk etc.
2. A person who fucks their mother.(Literal meaning)
Bob:That guy called me words and mocked me!
Jack:That guy must be a MotherFucker!
(Note: No offense meant for the usage of names:)
by TheWarProfessor May 19, 2015
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