a whore, a promiscuous female who engages in sexual activity with a lot of people who they have no relationship with.
by k_milly May 11, 2009
by Dzay June 2, 2007
A game residents of Terre Haute, Indiana play while driving through town. When you see someone you have to ask other people in the car, “Is that a tweaker?”. If you just guess yes, you are likely to be correct 75% of the time.
Turn on Locust Street, go a few blocks and when Donnie yells, “Is that a tweaker?” you’re in the right place.
What is that guy doing? Is that a tweaker?
What is that guy doing? Is that a tweaker?
by HairyGinger May 3, 2022
by Bigmike13 March 29, 2022
Someone who tinkers and adjust the setting of any object to make them perfect for their own purposes at that particular moment
by Pimpsnho's September 22, 2020
You can see a lot of these in Eugene Oregon . All though the true definition of tweaker is someone on meth but people can be on be tweakers with out meth sometime just weed and or alcohol. You will see most these people that non meth tweakers at night they smell like weed and dog shit and don’t listen to their papa. Common other name for tweaker is MILA( musty in lethal wAys)
by Lordoflandsinegpyt September 21, 2023