To be annoying to someone else, or to get someone else mad. Also used as the ultimate ponage word (even more affective then pwnzorafied1337h4xatroned).

The word, joe mama(x5), mainly conveys that you are not listening to someone else's negative, or worthless, comments.
Random man 1: Dude, sup homie corndog?
Random man 2: uhh.... nuttin' much, actually!
Random man 1: You know what? i had the most boring day in my life! I got pwoned by someone saying that im a pwoink! i--(keeps yammering, or talking trash....)
Random man 2 (in his head): *Joe mama joe mama joe mama joe mama joe mama joe mama..*
by Cauterize May 17, 2007
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Profanity that refers to the mom of the person on the receiving end.
Person 1: knock-knock..
Person 2: who’s there
Person 1: joe mama
Person 2: joe mama who?
Person 1: You fuckin’ little piece of sperm, yo suck a nigga dick or smthn? It’s yo mama.

Fuck u.
by yes7197 October 13, 2019
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A weird kinda Karen used in a roast battle and is used by 9 year olds and is used to trick people into saying joe who
Joe mama so fat
by Cheesiecheetos February 26, 2020
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Its is a meme where squidward is looking into your soul and then proceeds to say "Joe Mama"
Bro 1# whos joe
Bro 2# Joe Mama
by Avocatothot#69takashi October 21, 2019
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The great roast of a young individual who is a legend

It is played when someone shall play the card of joe

The other shall say joe who

Then the man the moth the legend shall respond with joe mama.

You are the most epic gamer if you shall play these cards.
Teacher *takes attendance*

Teacher “did i miss anyone’s name”
The man the moth the legend “oh you forgot joe
The teacher “joe who
The man the moth the legend “JOE MAMA
by CspGang November 8, 2019
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Joe mama
Joe mama
by Manuel🐜🦟 October 9, 2019
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