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Charlie Sheen 

A drug that if you try it once, you will die. Your face will melt off and your children will weep over your exploded body.
What is with you today?

I'm high on Charlie Sheen. #WINNER
Charlie Sheen by tigerblood March 18, 2011

Charlie Sheen 

"I'm on a drug. It's called Charlie Sheen."
-Charlie Sheen
Charlie Sheen by OshiA2 March 17, 2011

Charlie Sheen 

A drug that is highly addictive that offers a high lasting a lifetime.

Side effects include:

winning
tigers blood
melting of face
Charlie sheen: I'm on a drug. It's called Charlie sheen. If you tried it your face would probably melt off.

Reporter: ...

Charlie sheen: WINNING!
Charlie Sheen by Savvy6oh7 April 5, 2011

Charlie Sheen 

Noun: A mysterious and presumably potent drug named for its close association with American actor Charlie Sheen, its most famous user. Over-consumption may lead to wild, drug-fueled benders, failed marriages, and an alarming amount of time spent in the company of prostitutes and other questionable personalities.

Inexplicably, Charlie Sheen (the drug) does not show up on drug tests.

May also refer to a large joint packed with a wide assortment of drugs, including but not limited to: marijuana, opium, Ecstasy, heroin, cocaine, amphetamines, etc. A close relative to the Jeffrey.
"Yeah, I am on a drug - it's called Charlie Sheen." - Charlie Sheen

"I have one speed. I have one gear. Go!" - Charlie Sheen, under the influence of Charlie Sheen
Charlie Sheen by mind-fuck March 14, 2011

Charlie Sheen 

It's a drug. Only Winners take.
Kate: I heard that Tommy died this weekend. What happened?

Bob: I heard he tried some Drug called "Charlie Sheen" I guess his face melted off and his children were crying because his body exploded tiger blood all over the walls!!

Kate: Wow!! Crazy stuff.
Charlie Sheen by warlock11 March 19, 2011