Deceased; dead. Typically used to connote a potentially bad outcome. (Army slang)
"If you go AWOL, wwe're going to find you tits up in a ditch after Top hunts you down."
by Twathenge April 11, 2006
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Passed out in the street, typically from drunkeness or similar causes.
After his 16th beer, Freddie ended up tits up in the gutter.
by Figleaf23 June 15, 2007
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A hopeless situation that only gets worse, usually brought about by chance, and from which there appears to be absolutely no escape. bad luckf***** updead endno hope
Used in a fiction by Annie Proulx in the New Yorker June 9&16,2008
TITS-UP IN A DITCH,about the “luck” of a young woman,Dakota who was abandoned by her mother as a baby and raised on a farm by her grandparents. Her grandfather came back to the house one day and said that a cow had tried to climb a steep wet slope that apparently slid out from under her, and had landed on her back in a ditch. “Had me some (bad) luck today” he said. Goddam cow got herself tits-up in a ditch couple days ago. Dead time I found her”.
Dakota goes on to find herself pregnant, married and abandoned by her husband, Sash, who joined the army. Dakota then leaves her baby and also joins the army. Dacota lost an arm, her baby gets killed and Sash ends up in a coma with both legs blown off and half his head gone. Upon returning alone to the farm, Sash’s mother asks Dakota about his condition. Dakota answers “Sash is tits-up in a ditch”. And that is when Dakota began to feel her own decent into the dark watery mud.
by TuttPutt July 11, 2008
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This term is used when a red-neck or skid is on a motorized vehicle and crashes it to the point of being thrown off the machine.
"I was goin third gear wide open when that badger popped in front'a me, tried goin 'round the critter and ended TITS UP IN THE RHUBARB!"
by Ruban June 1, 2007
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1) A Chick with a fast car.

2) When a long term plan works out and everything goes smoothly as if it was written in a book.
1) The perky little blonde in the vintage Hemi Cuda passed me on the freeway doing at least 85 mph. She was tits up and wheelin.

2) The Alfster sat back and waited patiently for the fool to fall into his zealot rose trap. Soon, everything would be tits up and wheelin.
by Petergozinya September 22, 2009
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-Not just that you're fucked but that you're fucked AND it's still getting worse.

-Your life is in the shitter already and now some asshole is about to give you a spin & flush at least twice.

-Not only is your POS boat dead in the water but it's sinking as well
Guy1: well shit life sucks... My wife is cheating on me
Guy2: Umm dude, what's that letter from the health department?
Guy1: Fuck, I guess I'm just tits up and taking on water, she gave an STD too.
Guy2: Well, it could be worse.

Guy1: How's that?
Guy2: At least I haven't caught it from her yet.
by romaddeez March 4, 2010
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To have the courage and will to overcome a lack of motivation.
To become motivated.
"I don't feel like drinking beer tonight."
Man, Bobby, Tape those tits up, grow a sack, and drink a beer.
by Donny mallox August 16, 2017
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