basically means..Shit my Nigga..

all the other definitions 4 it on ere are wrong..
keisha: omg jason just got robbed!

jemal: shizzle my nizzle..lets kick yard an tell his brother
by xxitsstokesybabexx August 26, 2008
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To force someone to pay the money they owe you.
Mike:Shawn, isn't dat ur ho?
Shawn:Yeah, hey ho, shizzle-ma-nizzle!!
by ShawH. March 8, 2008
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This is a verb. To shizzle my nizzle means to take a salt shaker (aka shizzle) and have it expel its sodium-rich innards over someone's belly button. (aka navel, which leads to nizzle.) Shizzling someone's nizzle is a great sign of respect in many countries. Just don't do it in Italy. Ho boy... trust me.
He shook hands then shizzled my nizzle.
by The Me October 24, 2004
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Read backround written by Weeabix. But can also mean "for sure, my nizzle"
by Gibbo April 20, 2005
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a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African american brother."
"fo shizzle ma nizzle that is dank shit"
by yo mama's snatch March 15, 2003
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