Drunk and high. When a person drinks (one slice of bread) in combination with smoking (the other slice of bread), they become the ham sandwich.
Unsuspecting College Freshman1: "Hey man, lets get really high tonight."

More knowledgeable upperclassman: "Awesome, lets smoke your weed."

*Proceed to get really high*

Unsuspecting College Freshman2: "Hey guys, I bought beer from this homeless guy."

UCF1: "I can't turn down free beer, lets get drunk!"

MKU: "I'll sit this one out."

UCF1+2: Puke everywhere and die.

MKU: "Man, right before they died, they were totally ham sandwiched."
by Whothefuckk March 15, 2012
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Matt: holy hell dude, Sean was so ham sandwiched last night he knocked on people's door wearing a leopard print thong, asking for a cup of sugar. Then we ordered a pizza and ate an entire chocolate cake. I woke up on his couch, covered in BBQ sauce.

Tyler: HAMMED!
by motherbear August 25, 2008
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two pieces of bread with one or two slices of ham inbetween,
occasionally with a dollop of butter or margerine
hmm.... i'm hungry what shall i have for lunch?
oh! i know i'll have a ham sandwich!
by Angeli B. August 31, 2005
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The act of wanking between someones bumcheeks.
My bird gave me a ham sandwich last nite, but I also managed a sneaky pete
by pyrator April 25, 2003
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A Caucasian female that is less appetizing when compared to an exotic banquet.
Dave walked in to a fine Asian banquet, only to pull a Ham Sandwich out of the back pocket.
by Tower of power January 13, 2015
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