Made popular by iPwnstar4hire. When you get noob-tubed or pelted with coat hangers by your fiance. Often used as an expression
Fuck Knuckles. The whole team is tubing!
by TheBluestrype January 10, 2011
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Whoo-boy, yes sir, quite the riveting tale of rebellion and adventure indeed. I was on the edge of my goddamn seat I tell you what. That was some amazingly hot shit indeed, holy fuck knuckle son, I think I felt my dick move. You are clearly the greatest, baddest mother fucker to walk God's green Earth in the history of man. Four times you drove by with that horn? I am in goddamn awe. AWE I TELL YOU. Inspiring shit indeed, yes sir, there can be no question, you have really made a difference.
by beNZylpiperazine August 7, 2007
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When you see something so excessive, amazing, horrifying, fortuitous, or otherwise awesome, that you are bereft of any other words to say.
Scott: "That guy just walked out the flaming wreckage after a car accident!"
Bob: "Holy fuck knuckles! He is still walking!"
by pokettomonsuta November 20, 2017
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When a large mexican man shoves his knuckles violently in the (mexican) females vagina, and spins his hand around counter clock wise, as if he were opening a jar of jelly. Then he takes his other hand, and opens up more space to then stick his penis in and masturbate. with both hands.
what the fuck is with these crazy boarder hoppers doing all these mexican fuck knuckles in gas stations.
by Fuckin' lol November 14, 2011
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A large, shambling retard with a penchant to have things inserted in his rectum.
"There's one of those MV Fuck Knuckle"

"Damn he's ugly"

"I know...let's go kick him in the balls"
by DroolerZig November 2, 2011
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A term used to describe a person who is a general dumb-ass.
"Ernest is a real knuckle fuck" or "What a fucking knuckle fuck"
by nutsmell March 24, 2005
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