Probably the greatest freaking genius ever!!! An atheist and a supporter of gay rights who is best known for creating and voicing many of the characters in Family Guy, American Dad, and The Cleveland Show. Unfairly ridiculed for supposedly ripping off the Simpsons where, when you watch it is almost NOTHING like any of the shows he created (btw I love the Simpsons and am a fan). He also created a movie this year called Ted. MacFarlane has made people laugh for the past 13 years or so and always will.
Fred: Hey, what are you up to?
Ben: Watching Family Guy
Fred: Man I love that show it's so fucking funny!!
Ben: Ya I know
Fred: Doesn't Seth MacFarlane voice like 10 of the people in that show?
Ben: Yup
by Regina Phalange #2 November 20, 2012
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1. The creator/writer/cast member of Family Guy and some other stuff.

2. The cutest, funniest and most talented television personality of the 21st century.

3. 3rd greatest living voice actor (Dan Castenella is the 2nd and Billy West is the 1st)

4. My Hero and Crush.

5. Seth MacFarlane Syndrome; a slang term for people who are stupidly modest.
Look up Seth MacFarlane on youtube and watch a few vids, then maybe (if your not crazy) you'll like him
by simpuramafampark August 5, 2009
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An extremely talented voice actor and comedian who has made many worthwhile contributions to animated television sitcoms, most notably his creations: "Family Guy" and "American Dad."

Unfortunately, on a purely personal level, Seth MacFarlane is also one of the biggest douchebags who has ever lived. People slam celebrities like Marilyn Manson constantly, and say that he (Marilyn Manson) is basically one of the worst human beings that has ever been born. I would like to say that anyone who has ever met both Marilyn Manson and Seth MacFarlane can safely say that Seth is the bigger douchebag out of the two of them. Seth is a blatant misogynist who treats women like crap and gets away with it because people think he is handsome, funny and charming. Marilyn Manson isn't the nicest guy in the world either, but he is actually more sensitive, thoughtful and intelligent than Seth. He's also probably a better actor, and should audition for more film roles.

Seth MacFarlane also accuses others of being "gay" far too much, which probably means he is covering up his own latent homosexuality.
You should watch the "Family Guy" episode that deals with the issue of abortion. It's seriously one of the most insensitive things toward women ever. And there are far too many "gay jokes" in both "Family Guy" and "American Dad" to even name. In some ways, Seth MacFarlane's misogyny bothers me more than Marilyn Manson's music video for "Running to the Edge of the World." At the very least, they are both equally bad.
by anonymousxyz October 6, 2013
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One of the funniest/classiest men in the world. He created Family Guy and co-created The Cleveland Show and American Dad. He also produced the movie Ted. He is an Atheist. He is probably even more incredible than Harrison Ford... maybe.
Guy 1: Oh this show's so fucking hilarious!
Guy 2: That's because Seth Macfarlane made it!
Guy 1: Oh that guy's awesome!
by Some lady who likes this guy January 21, 2013
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lovely boy

what ever he is defenetly he made you laugh so its not ethical to chage your mind about him such cruly.
dont judge his beliefs.
its his own bussiness.
please respect such these people .
you will miss them surely after they gone.
please please show your love for him not to make him stop whatever he is doing right now.
enjoy him please

people: you have to continue your work seth.
seth:why?
people:because we wont make it without you. we love you all
seth macfarlane is a genius, lovely, talented voiceman filmmaker programmer and respecful man.
by lover of America June 23, 2018
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One of our generations most smart and funny influences.
Seth macfarlane is a funny mother fucker.
Ya but he's very smart and knowledgeable too.
by kstan3 September 27, 2010
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One of the most funniest and smartest people ever. Seth Macfarlane is the creator of Cleveland Show, American Dad, and his most popular show, Family Guy. People say Seth is untalented and has no ideas of his own. Well those people are dumb rednecks who think Obama is Hitler because he wants to give America health care. Seth rarely takes jokes from Simpsons, but other than that, he is pretty clever. You have to be smart to understand his humor, unfortunately Americans these days aren't smart so they don't understand his jokes.
Seth Macfarlane is really badass. It's a shame that the guys at FOX are dumb Republicans.
by barrelroll123 November 14, 2010
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