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painkillers 

drugs used to relieve pain. some are taken recreationally for their mind-altering effects, such as morphine, percocet, and vicodin.
eddie's doctor prescribed him some codeine-containing painkillers for his back pains, but eddie found himself still taking it long after his pain had went away.
painkillers by b-low July 24, 2006
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painkiller 

In Call of Duty: Modern Warfare 2 when someone dies multiple times in a row and has three time amount of normal health. Definitely the gayest of all death streaks. Usually occurs when your team is raping the shit out of the other team.
Guy 1:I tried to kill that guy, but he has has painkiller.

Guy 2:What a bitch..he sucks dick

Guy 1:Let's rape him anally.
painkiller by DirtyPugsley March 21, 2010

painkiller 

A video game for the pc
lets play some painkiller
painkiller by booshels June 5, 2005

painkiller 

When someone is shot in the skull.
He needs a painkiller.
painkiller by Andrew Briggs January 31, 2004

painkiller 

a drink made from rum, pineapple juice, coconut milk and sprinkled with nutmeg. the drink is popular in the caribbean and was purportedly created by the soggy dollar bar on jost van dyke in the british virgin islands.
if you drink too many painkillers, you won't be able to swim back to the boat.
painkiller by tfuro December 9, 2008

Painkiller drunk 

When you take painkillers, in relatively large doses and feel 'Drunk' as a result.
Man, I was up all night with a head ache, now I'm Tired High and Painkiller Drunk

pen island painkiller 

The act of soothing a girls headache by giving her an asprin, inserting your penis in her ear and thrusting back and forth until you climax, then she uses your sperm to help swallow the asprin.
Baby my migrane wont go away, will you give me a pen island painkiller.