Major League Shit.
A huge shit that you do, one that has possibly been stored up for a few days and then BAM you just explode from the ass.
Gavinda: Just had a chicken shit after that KFC pretty big.
KazZ: I haven't yet taken a crap bro.

3 days later...

KazZ: Dude just had the most epic MLS ever! That was one Major League Shit.
Gavinda: Nice bro.
by KazZ! August 6, 2011
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Mad Lesbian Syndrome: An identified medical condition in which signs of crankiness, up-tight attitude and utter prude-like bitchiness are commonly displayed on a regular basis around pretty much everyone
Laura: “Dude, Becca straight up denied my back-yard bbq invite for Dan’s birthday and sent me a message later that said she had more important things to do. What the hell, man?”
Dave: “Sounds like a bad case of MLS. Whatever. Her loss!”
by msbuttersworth August 11, 2011
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Major League Stoner: A person very experienced in the usage. or smoking of marijuana, or someone who has smoked weed for a long period of time becoming an a master/expert on subjects regarding marijuana , such as potency and strains, as well as market pricing and other such subjects related to marijuana, and its use.
My friends is a MLS ,a major league stoner, he smokes all day everyday. You need to know something about weed you go to him, he's an expert.
by PhillyAppleKY August 10, 2010
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Massive Loser Squad................
Righhhtttttttttttttttttttttttttt right right
by Scott Chode February 2, 2005
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Moon Light Strkangers.....
Crab and Raskal killers from Lowell MA...

Close affiliation with DLB and DC..
MLS rocking your way kuh....
by YG Blood October 7, 2004
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"Minty Lip Shine"

Mint-flavored clear lipgloss from heaven, as seen overpriced at Victoria's Secret.
"Mmmm, this MLS tastes great... totally worth the $30 I paid for it!"
by The Minty Lip Fairy October 15, 2008
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