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A commonly used catchphrase by Southern California queens, especially Hillcrest betches meaning "Oh Shit Girl."

This abbreve (abbrebiation) has also made its way onto many t-shirts and is funniest when used with a very girly man or woman.
Did you see that fired-ass tranny walking across the street?

"OSG"
osg by ParisFired January 5, 2010
Related Words
OSG Osgiliath osgal Osgarism Osgerby osgiliate osglitternoob Osgm osgo osgood
original stoner group. The original group of people you started smoking with. Coined in the Bay Area, if you know it, your in.
Mark: Hey man want to hang out?
Jake: Can't, hanging with the OSG tonite...
Mark: Damn, wish I had one.
OSG by JTKL January 8, 2013
A guy who is kind hearted and unique. OSG is one of a kind
Currently OSG is in Delta State University, Abraka.(DELSU)
OSG by OSG™ March 11, 2023
Old School Gamer (or Old Skool Gamer)
a Person who prefers old Games instead of new games
basically another word for retrogamer that was originated in a Dirty South Killa Song where he mentioned many Sega and Nes Games.
MAN1:"what are you playing"
MAN2:"super mario bros"
MAN1:"oh an OSG classic"
MAN2:"I am OSG so I love these kinds of games"
OSG by JD West May 6, 2008
OSG is a Unique and Generous
OSG is currently in Delta State University, Abraka (DELSU)
OSG by OSG™ March 22, 2023

Osgood-Schlatter's Disease 

Osgood-Schlatter disease (also known as tibial tubercle apophyseal traction injury) is an inflammation of the growth plate at the tibial tuberosity, and is one of a group of conditions collectively called osteochondroses. The condition is named after the American surgeon Robert Bayley Osgood (1873–1956) and the Swiss surgeon Carl Schlatter (1864–1934), who independently described the disease in 1903.

The disease is most common in active boys and girls aged 11-15 and is usually self-limiting


Causes
The condition is caused by stress on the patellar tendon that attaches the quadriceps muscle at the front of the thigh to the tibial tuberosity. Following an adolescent growth spurt, repeated stress from contraction of the quadriceps is transmitted through the patellar tendon to the immature tibial tuberosity. This can cause multiple subacute avulsion fractures along with inflammation of the tendon, leading to excess bone growth in the tuberosity and producing a visible lump.
Osgood-Schlatter's Disease

-Dude, What is that huge ass lump on your knee??

-Oh that is just my Osgood-Schlatters Disease also known as jumpers knee

-sweet