A girl who gets pregnant the first time she has sex with each new partner.
Friend 1: Did you hear about Jane? She had an abortion a few months ago, then started dating John and is already pregnant again!

Friend 2: Yeah, she’s a one shot sally.
by theMambo August 25, 2020
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Where you use something once, and it gets the job done.
David is a one shot sally. Damn this one gun in MW3 that only reloads once in a lifetime but kills a butt load of kids in one shot is a one shot sally.
by One-Shot sally February 25, 2012
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