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Struggle Bus 

Used to metaphorically describe a difficult situation, as in hard schoolwork.

The word struggle can also be used in conjunction with other modes of transport, describing the depth to which one is struggling(i.e. struggle scooter, struggle skateboard, struggle footwear).
Student: "Y'all, I have 6 papers and 4 tests within the next 2 weeks. Definitely on that struggle bus!"
Struggle Bus by VADyme April 16, 2009

struggle bus 

A generic conceptual term for the vehicle or conveyance used to get to work or school after a late night of partying, especially when accompanied by a hangover.
- Carly looks like shit!
- Yeah, she took the struggle bus into work today.
struggle bus by G-Money December 9, 2008

Struggle Bus 

Phrase used by the upper middle class to imply that they have a difficult life.
"I'm on the struggle bus. My dad bought me the wrong color iPhone."
"I'm on that struggle bus because one of my six beach houses was destroyed by hurricane Sandy."
Struggle Bus by The One, The Only August 25, 2013

Struggle Bus 

When retailers can't keep up with the rest of the stores and seem to be failing. (In need of some help)
Eddie Bauer just filed for bankruptcy. It's offical, they are on the struggle bus.
Struggle Bus by hoolahoop57 July 13, 2009

Struggle Bus 

Phrase used when you and your friends are high as fuck and one friend is laughing uncontrollably at something.

Is usually said in a high pitched patronizing way to make the person struggle even harder.
Fred: PINEAPPLE HAHAHA AAAHAHAHAHAHA

Jim: STRUGGLE BUS!

John: STRUUUUGLE BUUUUS!!!

Fred: BAAHAHAHA *Gasp* XD PFFTNNHAHAHAHAHAHAHA

struggle bus 

An off color reference to the bus ridden to school specifically for the handicapped kids.
you're such a dumbass, you ought to have your own seat on the struggle bus with the rest of them