SMATHOE Share definition Flag A whore. A slut. Some one who has sex with everyone..Word originated in brooklyn 90z by a group Called HH. Yow Cuz. Lets go on da ave and look for some SMATHOES I need some neCC SMATHOE by giftgiver December 20, 2010 0 0 Get merch Get the SMATHOE mug. Buy Now — $32.95 See more merch