the act of a female giving someone sex.
dont waste your time or money on that bartender the only one shes giving it up to is her boyfriend the bouncer.
by tellitizaman September 15, 2010
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to cheer for someone, or what they bring to the game
Give it up to your dj on the 1-2s keepin it crunk for the party
by DJ Kayla March 1, 2004
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to give in to one's sexual urges in a quick manner; usually referring to females
dang i was with abby for 10 mintes when she was ready to give it up!
by the give it upper March 3, 2004
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A request for praise which can be issued either by the recieving party or a third party.
Give it up for my man DJ Mike!
by Spirit Bear February 28, 2004
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To cease efforts now otherwise pointless
"Just give it up man, she's not interested in you."

"You'd better give it up, unless you're rollin' for a bitch-slap."
by Krispy February 29, 2004
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You're not getting your money till you give it up.
by Anonymous June 17, 2002
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