when you have bumps and or pimples on your legs that look less than appetizing...
"Did you see that girl over there?"-- random guy
"The blond one?"-- his girlfriend
"Yeah... it looks like she has herpesyphagonnalegs, those bumps dont look like they are supposed to be there"-- random guy ---*looks over at her legs*"Ewww!!! It does she looks nasty." his girlfriend