1 definition by uhhuhman

Up and Down reffers to cocaine (Up) and heroin. (Down)
"Yo let me get 5 up and 10 down."

Buyer- "Hey papi, do you got both up and down?"
Dealer- "Yes!"
Buyer- "Awesome! Let me get 7 up, 10 down."
Dealer- "That's 170 papi."
by uhhuhman February 12, 2021
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