1 definition by thegregman

Top Definition
The unfortunate situation when two groups of biddies that you have been hanging out with separably finally meet each other and the lines of communication open. Just like when Columbus found North America and the Western and Eastern hemisphere exchanged large amounts of communicable disease.
Hey man don't tell Shaniqua that we are going out tonight because Lashonda will be out too, we do not want another Columbian Exchange.
by thegregman April 26, 2012
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