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2 definitions by chocolatemonster

 
1.
a slang term for marijuana originating from the Midwest, referring to the Native American custom to use every part of the buffalo.
"Save the stems of that buffalo, dude, we can use it later."

"Yo, dude, pick that nug up, you can't waste the buffalo."

"Dude, don't cash that buffalo yet, you can't waste the buff."
by chocolatemonster March 31, 2009
 
2.
A slang term for marijuana, coming from the original slang buffalo, which refers to the Native American custom to save all parts of the buffalo.
"Yo, dude, pass the buff."

"Hey, dude, pick all of that weed up! You can't waste the buff like that!"
by chocolatemonster April 24, 2009