Contrary to the movie Anchorman: The Legend of Ron Burgundy, San Diego is far from Airhead City, USA. Not all San Diegans are po-dunk locals who have never been anywhere else. And it's true, the city is really one of the better ones out there, despite the lack of San Fran-esque transportation and the similar.
San Diego's good weather attracts lots of tourists, but very few of those outsiders know more than the downtown. We do have funky/ethnic neighborhoods, Old Town places, and the similar. But only locals know about it.
I've lived in San Diego for 8 years, and I've lived many other places. It's the best so far.