1 definition by TXwolfman817

Desiganted Ugly Fat Friend. A common acronym used in male cliques. Used to refer to the girl that the "hot chicks" bring along to distract the "Wingman" (every male clique has one, his job is to intercept the DUFF.) so the ycan have the more desirable males of the group.
"Dude, you sooooo got the DUFF tonight."
by TXwolfman817 October 21, 2008
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