1 definition by SteveJeffDunhamBuscemi

1) The area code for the area of the country with the largest number of meth busts, located in Southwest Missouri.

2) Someone who looks like they do meth.

3) Slang for crystal meth.

4) this is Clay and Billie’s homeland.
1) They got another bust in the 417 today.

2) Sarcasm: Wow, she's not from the 417 or anything.

3) Dude, can I score some 417?
by SteveJeffDunhamBuscemi April 13, 2018
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