1 definition by Smart Nigga 18
a confusing and impossible to understand situation or place. Very complex. Only nerdy niggas will have a chance to understand a mysterium. Everybody else don't even try, your head will explode.
James: "Yo Will, girls are a mysterium. I'm trying to figure out why they crazy as hell"
Will: "You better stop man before your head explodes. Shit's crazy"
Will: "You better stop man before your head explodes. Shit's crazy"
by Smart Nigga 18 July 27, 2008