1 definition by Slipspace

When you mix up Rohypnol and Cannabis and smoke it
in a gravity bong and then pass out on the floor.
Dude 1: Dude, i got so fucked up last night. i smoked some Ro and weed,
cuz i thought i could handle it but that shit was fo' real man. i got totally twitknocked!

Dude 2: Hahaha dude, you serious? i gotta try that!
by Slipspace November 11, 2010
Get the Twitknock mug.