The patch of skin between the asshole and the balls; also known as the chode
Johnny was bent over looking at somthing on the ground, so I ran up and kicked him as hard as I could right in the sweet spot.
(1) A massive asshole (figuratively)
(2) A massive asshole gaper
Other than colloquial or local usages, his word has nothing to do with the State of Massachusettes.
(1) Jimmy stole three dollars out of my wallet to buy a cheese sub; he's a masshole.
(2) Wehn I first saw the size of her brown-eye, I almost exclaimed "That's a masshole."