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1 definition by Michael Shmidt

Laughing uncontrollably, sometimes for hours on end. Often results in the person pissing their pants, and or soiling themselves. It is considered a disease by certain countries, with no cure in sight.

First case was discovered in a small town known as Marshfield
Byron: Oh no, I think Maria has the gunkles.

Markie: Oh god, somebody get some air sanitizer and some toilet paper!
by Michael Shmidt March 30, 2009
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