The term used for when you have a grandmother who likes to play MMORPG's, such as World of Warcraft, Rift, Everquest, and Hammer Online. These grannies can be dangerous, as sometimes they forget that they are in real life, not the game...
Bob: "Dude, is your grandma playing WoW???"
Dave: "Yea, she's a pretty hardcore MMORPGranny!"
Kam: "No grandma! Not the sword! This is real life, I wont give you loot! Your such an MMORPGranny!"
Grandma: "Die goblin!"