1 definition by MC K-Khan

Gay Buddy Syndrome
as first coined by Viko Suave, refers to becoming close friends with a member of the opposite sex who is already in a relationship, in hopes of one day having intercourse or hooking up with that person.
Ricky is going shopping with Rachel while her boyfriend is gone for the weekend...that dude has some mad GBS!

Dude I have to get dinner with this girl I know... man it's fucking GBS!

Neil has massive GBS for Beth! Someone call the doctor!
by MC K-Khan February 10, 2006
Get the GBS mug.