Pronounced either Kwee-Kwee or Kwa-Kwa, it is a common response to when somebody (usually a guy) says or does something gay.
(Mark, Mike, Jake and Ben sitting in the living room.)
Mike: "What should we do tonight?"
Ben: "I dunno, I'm kinda bored. Maybe we should go stargazing..."
Mike, Mark, and Jake: "Que-Que."