1 definition by Histprof

Derogatory term/ slang used in reference to a person from the Gary-Hammond metropolitan area of Northwest Indiana. Origin of the word is either a reference to the high amounts of pollution or unique patchwork culture that "Mutates" its inhabitants. Although the term's creation was intended to insult it is now used as a term of endearment among residents.
Yea, he works in Chicago, but he's a mutant
by Histprof December 13, 2010
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