1 definition by Hew Shin Po
The abbreviation MSF stands for "Male seeking female." This useful shorthand is used by online chat-room dwellers at random chat websites such as Omegle often in place of a greeting. By messaging MSF one clearly states to the other chatters they are a male interested in females. A female may also use the similar abbreviation FSM, or "Female seeking Male."
by Hew Shin Po January 29, 2014