2 definitions by GamingFanatic

(Not to be confused with one of several keys on a piano or related instrument)

Possibly the most versatile and ubiquitous button on a computer's keyboard performs all of the following with standard Macros:

Opens inventory in MineCraft
Calls for the Medic in Team Fortress 2
Picks up an item in any Source Engine game that is not TF2
Lets you travel faster than a pathetic crawl in Oblivion
Picks up carry-able items in the Borderlands Games
Opens chat in some multiplayer games (though far less common than T, Y, U, or C)

And if you're not a gamer, It does provide one other function, it is the second most commonly typed key in normal text editing, second only to the space bar (including Word, Facebook, Twitter, and even right here on Urban Dictionary.)
I hate it when someone keeps spamming the E key in Team Fortress 2.
The puzzles in Portal and Half Life are fun as long as you have a functioning E key.
This sentence uses the E key eleven times.
by GamingFanatic June 21, 2014
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A statement notifying people in certain multiplayer PC games (Most notably in Team Fortress 2's Mann V. Machine game mode) to ready up for purposes of a match starting. So named because the Function-4 (F4) key starts (or reduces time of) a countdown timer for an MvM wave. Usually used for the following reasons...

1. A teammate notices a sufficiently prepared teammate who has yet to press f4 and notifies them as such.

2. An impatient scrubby try-hard 20-something who can't wait 2 1/2 minutes for a wave to start shouts it into the microphone.

3. A N00B 10-14 year-old who thinks s/he's helping when almost everyone knows about it. (often shouting into the mic in a nasally pre-teen voice.

Inversions usually occur in the following situations...

1. An engineer tells his/her team to stop the countdown so s/he can prepare sufficiently. (A competent MvM engineer can get all 4 (or 5) of his buildings ready in about 30 seconds. (usually about 50 remain after 5/6 readies))

2. A teammate needs time to figure out upgrades. (Upgrade priorities are often common sense (metal and building health upgrades for engie, UberCharge upgrades for medic, resistances and speed for scout, afterburn effectiveness for pyro, etc. with slight variance for map and loadout.)
The Engineer on our team had all of his buildings up and in tactical locations, so I told him to press f4.
I was very tempted to mute the annoying noob for spamming press f4 in his whiny pre-teen voice.
by GamingFanatic June 21, 2014
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