Simply put, a slut. A big, whorish, delta zeta slut. Not just your regular slut though, these are the girls who leave you "itching" NOT for more.
Plural; Slues. Used most commonly by frat boys who learn their lesson the hard way, or the by the smart ones who know to keep at least 100 yard away at all times (especially during mating season - those turtles really want to get theirs.)
"Yo dude, i woke up this morning with a burning sensation"
"dude, did you sleep with a dz?"
"fuck. what a slu."