1. A series of video games created by Satoshi Tajiri for the Nintendo Game Boy. Pokémon literally invented the turn-based R.P.G. genre, so if you play Final Fantasy or any other turn-based game, you might have Pokémon to thank for that.
Many consider it to be quite childish. Sure, the games and such are directed to a young demographic, but many teenagers and adults play it as well. There's even an entire Cheezburger website dedicated to Pokemon-themed image memes and videos!
2. The creatures in the Pokémon games themselves. Notable examples include Pikachu, Jigglypuff, and Squirtle.
The word is often misspelled "Pokemon", without the accent on the E. It's often spelt like this because most North American keyboards do not have an "é" key, just an "e".
1. Person A: I like Pokémon.
Person B: Lol, fag. Final Fantasy is better.
Person A: (stunned look)
2. Pokémon are fictional animals created for the Pokémon video game series. As of January 2012, there are 649 (!) Pokémon, from Bulbasaur to Genesect.