- Occurs when someone sees something very obscure, such as a bag of Doritos, and experiences a moment of enlightenment, inspiration, or revelation
- Derived from when Gregory House, M.D. suddenly diagnoses a patient while not being in the same room space and usually when talking about trying to have sex with Dr. Lisa Cuddy with Dr. James Wilson, his only friend or when watching television and playing with his one red and blue ball
House and Wilson are walking down the hallway and Wilson comments on House's use of prostitutes. House is about to retort with a smartass comment when he realizes his patient has Trichomonas vaginalis, which is a Sexually Transmitted Disease. Wilson's comment involving prostitutes was House's, Bag of Doritos.