1 definition by Doug Russel aka "Knuck Duster"
an ailment that may occur the morning after you have smoked. Symptoms are dehydration (yet unwillingness to rehydrate one's self), excessive complaining, and clumsiness. Often affects annoying people and non-regular smokers.
"I'm telling you the weed made me sick man!
Bullshit, you've got Marijuana Syndrome."
"Fucking Michael dropped a glass jar of salsa on your driveway when he was getting into his dad's car earlier.
I knew that nigger had Marijuana Syndrome."
by Doug Russel aka "Knuck Duster" Sep 20, 2010 add a video