an ailment that may occur the morning after you have smoked. Symptoms are dehydration (yet unwillingness to rehydrate one's self), excessive complaining, and clumsiness. Often affects annoying people and non-regular smokers.
"I'm telling you the weed made me sick man!

Bullshit, you've got Marijuana Syndrome."

"Fucking Michael dropped a glass jar of salsa on your driveway when he was getting into his dad's car earlier.

I knew that nigger had Marijuana Syndrome."
by Doug Russel aka "Knuck Duster" September 21, 2010
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MDS is a severe neurophysical and behavioral disorder characterized by a lack of marijuana in one's system. Victims of MDS exhibit a tendency to buzzkill, harsh on good times, and induce downer vibes. MDS is treatable, but not curable.
The Federal Government's raid on Oaksterdam University suggest that Obama may be suffering from Marijuana Deficiency Syndrome (MDS).
by Fred Quick May 9, 2012
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